High flow oxygen therapy has a unique physiological effect and widely used clinically to acute hypoxic respiratory failure, post-tube oxygen therapy, acute heart failure, chronic airway disease and some airway invasive manipulation. Especially to acute hypoxic respiratory failure patient, HFNC has obvious advantage in increasing PO2 than traditional oxygen therapy and better effect than NIV, also in comfort and tolerance. However, HFNC is recommended to be first choice respiratory treatment method for such patients.
Initially, HFNC is intended as an alternative supporting methods to NCPAP to be widely used for neonatal respiratory distress syndrome (NRDS), and obtained positive effect. HFNC application on adult has recognized the specific advantage during usage compared to usual oxygen therapy and non-invasive mechanical ventilation (NIV).
